Citrullinated Fibrinogen monoclonal antibody, clone 3D1

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Citrullinated Fibrinogen monoclonal antibody, clone 3D1

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Data sheet of Citrullinated Fibrinogen monoclonal antibody, clone 3D1

Brand	Abnova
Product type	Primary antibodies
Reactivity	Mouse
Host species	Mouse
Applications	ELISA

More info about Citrullinated Fibrinogen monoclonal antibody, clone 3D1

Brand:	Abnova
Reference:	MAB5303
Product name:	Citrullinated Fibrinogen monoclonal antibody, clone 3D1
Product description:	Mouse monoclonal antibody raised against synthetic peptide of Citrullinated Fibrinogen.
Clone:	3D1
Isotype:	IgG1
Immunogen:	A synthetic peptide corresponding to mouse Citrullinated Fibrinogen.
Form:	Lyophilized
Recommend dilutions:	The optimal working dilution should be determined by the end user.
Storage buffer:	Lyophilized from 10 mM ammonium bicarbonate buffer
Storage instruction:	Store at 4Â°C on dry atmosphere. After reconstitution with deionized water, store at -20Â°C or lower. Aliquot to avoid repeated freezing and thawing.
Product type:	Primary antibodies
Host species:	Mouse
Antigen species / target species:	Mouse
Specificity:	Fibrinogen is a protein produced by the liver which helps stop bleeding by helping blood clots to form. Fibrinogen gets deiminated (conversion from arginin to citrullin) by Peptidyl Arginine Deiminase (PAD) in inflamed joints in patients that develop rheumatoid arthritis. Citrulline, while being an amino acid, is not built into proteins during protein synthesis, as it is not coded for by DNA, yet several proteins are known to contain citrulline. Proteins that normally contain citrulline residues include myelin basic protein (MBP), filaggrin, and several histone proteins, while other proteins, like fibrin and vimentin can get deiminated during cell death and tissue inflammation. Patients with rheumatoid arthritis often (at least 80% of them) develop an immune response against proteins containing citrulline.
Reactivity:	Mouse
Applications:	ELISA
Shipping condition:	Dry Ice

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