Brand | Abnova |
Product type | Primary antibodies |
Reactivity | Human |
Clonality | Monoclonal |
Host species | Mouse |
Applications | IP,IHC-Fr,Flow Cyt |
Product description: | Mouse monoclonal antibody raised against native CD180. |
Clone: | MHR73 |
Isotype: | IgG1 |
Gene id: | 4064 |
Gene name: | CD180 |
Gene alias: | LY64|Ly78|MGC126233|MGC126234|RP105 |
Gene description: | CD180 molecule |
Immunogen: | Native purified CD180 from M12HRP cell line. |
Form: | Liquid |
Recommend dilutions: | Flow Cytometry (10ul of the suggested working dilution (1:50-1:100) to label 106 cells in 100ul) The optimal working dilution should be determined by the end user. |
Storage buffer: | In PBS (0.09% sodium azide) |
Storage instruction: | Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing. |
Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Specificity: | This antibody recognizes human CD180 (RP105) a 105kD type 1 transmembrane protein, which belongs to the toll-like receptor family. CD180 is primarily expressed in mature peripheral B cells and is thought to play a role in the innate immune response to bacterial lipopolysaccharide, through co-operation with MD-1 and TLR4. Cross linking of CD180 with clone MHR73 has been reported to induce resistance against irradiation induced apoptosis, B-cell proliferation and up-regulation of a co-stimulatory molecule CD80. |
Size: | 200 ug |
Shipping condition: | Dry Ice |