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Data sheet of GPIIb/IIIa complex monoclonal antibody, clone CLB-48
| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Host species | Mouse |
| Applications | IF,Flow Cyt |
More info about GPIIb/IIIa complex monoclonal antibody, clone CLB-48
| Brand: | Abnova |
| Reference: | MAB5226 |
| Product name: | GPIIb/IIIa complex monoclonal antibody, clone CLB-48 |
| Product description: | Mouse monoclonal antibody raised against native GPIIb/IIIa complex. |
| Clone: | CLB-48 |
| Isotype: | IgG1 |
| Immunogen: | Native purified GPIIb/IIIa complex from human platelets. |
| Form: | Liquid |
| Recommend dilutions: | The optimal working dilution should be determined by the end user. |
| Storage buffer: | In 20 mM Tris, 150 mM NaCl, pH 8.0 (10 mg BSA, 0.001% thimerosal) |
| Storage instruction: | Store at 4°C. |
| Note: | This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Antigen species / target species: | Human |
| Specificity: | Apparent molecular weight under reducing conditions: GPIIIa; 110kD; GPIIb alpha chain; 125 kD, beta chain; 25kD. The monoclonal antibody recognizes the intact platelet GPIIb/IIIa complex, i.e. it does not bind to dissociated GPIIb or GPIIIa. This antibody reacts with human trombocytes and megakaryocytes. This antibody does not bind to platelets from patients with Glanzmann thrombasthenia and does not recognize the vitronectin receptor, which contains GPIIa as a beta subunit (cf. CD61). The monoclonal antibody activates human thrombocytes and induces thrombocyte aggregation in the absence of trombocyte inhibitors such as EDTA. |
| Reactivity: | Human |
| Applications: | IF,Flow Cyt |
| Shipping condition: | Blue Ice |