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Data sheet of HLA-DR1 monoclonal antibody, clone MEM-267 (PE)
| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Host species | Mouse |
| Applications | Flow Cyt |
More info about HLA-DR1 monoclonal antibody, clone MEM-267 (PE)
| Brand: | Abnova |
| Reference: | MAB5091 |
| Product name: | HLA-DR1 monoclonal antibody, clone MEM-267 (PE) |
| Product description: | Mouse monoclonal antibody raised against HLA-DR1. |
| Clone: | MEM-267 |
| Isotype: | IgG2b |
| Immunogen: | Purified, insoluble DR1 beta chain (DRB1*0101) expressed in Escherichia coli inclusion bodies. |
| Form: | Liquid |
| Concentration: | 0.1 mg/mL |
| Recommend dilutions: | Flow Cytometry (5 ug/mL) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In PBS (0.2% BSA, 0.09% sodium azide) |
| Storage instruction: | Store in the dark at 4°C. Do not freeze. Avoid prolonged exposure to light. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Conjugate tag: | PE |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Antigen species / target species: | Escherichia coli |
| Specificity: | This antibody specifically binds to the empty but not peptide-loaded form of HLA-DR1. DR is the isotypes of human MHC Class II molecules expressed on antigen-presenting cells (APC; dendritic cells, B lymphocytes, monocytes, macrophages). |
| Reactivity: | Human |
| Applications: | Flow Cyt |
| Shipping condition: | Blue Ice |
| Publications: | Monoclonal antibodies specific for the empty conformation of HLA-DR1 reveal aspects of the conformational change associated with peptide binding.Carven GJ, Chitta S, Hilgert I, Rushe MM, Baggio RF, Palmer M, Arenas JE, Strominger JL, Horejsi V, Santambrogio L, Stern LJ. J Biol Chem. 2004 Apr 16;279(16):16561-70. Epub 2004 Feb 2. |