Brand: | Abnova |
Reference: | MAB4873 |
Product name: | KLKB1 (Heavy Chain) monoclonal antibody, clone 901 |
Product description: | Mouse monoclonal antibody raised against native KLKB1 (Heavy Chain). |
Clone: | 901 |
Isotype: | IgG1 |
Gene id: | 3818 |
Gene name: | KLKB1 |
Gene alias: | KLK3|PPK |
Gene description: | kallikrein B, plasma (Fletcher factor) 1 |
Immunogen: | Native purified human plasma KLKB1 (Heavy Chain). |
Form: | Liquid |
Recommend dilutions: | The optimal working dilution should be determined by the end user. |
Storage buffer: | In PBS, pH 7.4 |
Storage instruction: | Store at -20°C. Aliquot to avoid repeated freezing and thawing. |
Product type: | Primary antibodies |
Host species: | Mouse |
Antigen species / target species: | Human |
Specificity: | Recognizes two variants (88 KDa and 85 KDa) of prekallikrein and its activation products kallikrein (88 KDa and 85 KDa), the complexes formed by kallikrein with its endogenous inhibitors C1 inhibitor, alpha-2-macroglobulin and Antithrombin III, and 45 KDa prekallikrein/kallikrein fragment(s). Recognizes prekallikrein and its activation products in human, chimpanzee, rhesus, and baboon plasmas. The epitope for this antibody, located on the prekallikrein/kallikrein heavy chain, is involved in the interaction between prekallikrein and factor XIIa. This antibody inhibits prekallikrein activation in human and rhesus plasmas by approximately 60-80% and 55%, respectively. This antibody does not cross-react with tissue kallikrein. |
Reactivity: | Baboons,Chimpanzee,Human,Monkey |
Applications: | WB,ELISA |
Shipping condition: | Dry Ice |