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Data sheet of CD29 (VLA B1), 130kDa, Integrin beta 1 chain monoclonal antibody, clone Lia1/2
| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Host species | Mouse |
| Applications | IHC,IF,Flow Cyt |
More info about CD29 (VLA B1), 130kDa, Integrin beta 1 chain monoclonal antibody, clone Lia1/2
| Brand: | Abnova |
| Reference: | MAB4731 |
| Product name: | CD29 (VLA B1), 130kDa, Integrin beta 1 chain monoclonal antibody, clone Lia1/2 |
| Product description: | Mouse monoclonal antibody raised against native CD29 (VLA B1), 130 KDa, Integrin beta 1 chain. |
| Clone: | Lia1/2 |
| Isotype: | IgG1 |
| Immunogen: | Native purified CD29 from U937 myelomonocytic cells. |
| Form: | Lyophilized |
| Recommend dilutions: | Immunofluorescence (2ug/5x105 cells) Flow Cytometry (2ug/5x105 cells/test) Immunohistochemistry (1:25-1:50) The optimal working dilution should be determined by the end user. |
| Storage buffer: | Lyophilized from PBS (1mg/mL BSA) |
| Storage instruction: | Store at 4°C on dry atmosphere. After reconstitution with deionized water, store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Specificity: | The molecular weight of the recognized antigen is 130KDa. CD29 is the integrin B1 chain which is expressed as heterodimer non-covalently associated with the integrin alpha subunits 1 to 6 (CD49a to CD49f) and known as very late antigens (VLA). It is also called platelets GPlla. It has been reported as receptor of fibronectin. The antigen mediates cellular adhesion. It has a broad cellular reactivity but is not expressed by erythrocytes. In normal peripheral blood CD29 is found on approximately 41% of T cells, 40% of CD4+ T lymphocytes, 43% of CD8+ T lymphocytes (1). It is slightly reactive with peripheral B-cells (1). The coexpression of CD4 and CD29 allows the identification of the helper/inducer subpopulation of CD4 lymphocytes. Clone Lia1/2 is a blocking antibody. |
| Reactivity: | Human |
| Applications: | IHC,IF,Flow Cyt |
| Shipping condition: | Dry Ice |
| Publications: | Abnormalities of T lymphocyte subsets in Behcet's disease demonstrated with anti-CD45RA and anti-CD29 monoclonal antibodies.Kahan A, Hamzaoui K, Ayed K. J Rheumatol. 1992 May;19(5):742-6. |