Brand | Abnova |
Product type | Primary antibodies |
Reactivity | Human |
Host species | Mouse |
Applications | IHC-Fr,IF,Flow Cyt |
Brand: | Abnova |
Reference: | MAB4658 |
Product name: | CTLA4 monoclonal antibody, clone BNI3 |
Product description: | Mouse monoclonal antibody raised against recombinant CTLA4. |
Clone: | BNI3 |
Isotype: | IgG2a |
Gene id: | 1493 |
Gene name: | CTLA4 |
Gene alias: | CD152|CELIAC3|CTLA-4|GSE|IDDM12 |
Gene description: | cytotoxic T-lymphocyte-associated protein 4 |
Immunogen: | Recombinant protein corresponding to human CTLA4. |
Form: | Lyophilized |
Recommend dilutions: | Immunofluorescence (2ug/5x105 cells) Flow Cytometry (2ug/5x105 cells/test) Immunohistochemistry (Frozen sections)(5-50 ug/mL) The optimal working dilution should be determined by the end user. |
Storage buffer: | Lyophilized from PBS (1mg/mL BSA) |
Storage instruction: | Store at 4°C on dry atmosphere. After reconstitution with deionized water, store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
Product type: | Primary antibodies |
Host species: | Mouse |
Antigen species / target species: | Human |
Specificity: | Recognizes CD152 (CTAL-4). The "cytolytic T-lymphocyte-associated antigen 4" (CTLA-4) is a member of the Ig superfamily (1) and its extracellular domain exhibits a single Ig V-like region. It was originally identified as a fourth cDNA product, during a search for genes that were thought to be specifically expressed in cytotoxic T lymphocytes (1). CTLA-4 has a molecular weight close to 45KDa (2). It is mainly expressed as a monomer (4), but may also be expressed as a disulfide-linked homodimer (2,3). CTLA-4 belongs to the CD28 receptor family (4,5). |
Reactivity: | Human |
Applications: | IHC-Fr,IF,Flow Cyt |
Shipping condition: | Dry Ice |
Publications: | Lymphocyte activation: T-cell regulation by CTLA-4.Linsley PS, Golstein P. Curr Biol. 1996 Apr 1;6(4):398-400. |