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CTLA4 monoclonal antibody, clone BNI3

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Data sheet of CTLA4 monoclonal antibody, clone BNI3

BrandAbnova
Product typePrimary antibodies
ReactivityHuman
Host speciesMouse
ApplicationsIHC-Fr,IF,Flow Cyt

More info about CTLA4 monoclonal antibody, clone BNI3

Brand: Abnova
Reference: MAB4658
Product name: CTLA4 monoclonal antibody, clone BNI3
Product description: Mouse monoclonal antibody raised against recombinant CTLA4.
Clone: BNI3
Isotype: IgG2a
Gene id: 1493
Gene name: CTLA4
Gene alias: CD152|CELIAC3|CTLA-4|GSE|IDDM12
Gene description: cytotoxic T-lymphocyte-associated protein 4
Immunogen: Recombinant protein corresponding to human CTLA4.
Form: Lyophilized
Recommend dilutions: Immunofluorescence (2ug/5x105 cells)
Flow Cytometry (2ug/5x105 cells/test)
Immunohistochemistry (Frozen sections)(5-50 ug/mL)
The optimal working dilution should be determined by the end user.
Storage buffer: Lyophilized from PBS (1mg/mL BSA)
Storage instruction: Store at 4°C on dry atmosphere.
After reconstitution with deionized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.
Product type: Primary antibodies
Host species: Mouse
Antigen species / target species: Human
Specificity: Recognizes CD152 (CTAL-4). The "cytolytic T-lymphocyte-associated antigen 4" (CTLA-4) is a member of the Ig superfamily (1) and its extracellular domain exhibits a single Ig V-like region. It was originally identified as a fourth cDNA product, during a search for genes that were thought to be specifically expressed in cytotoxic T lymphocytes (1). CTLA-4 has a molecular weight close to 45KDa (2). It is mainly expressed as a monomer (4), but may also be expressed as a disulfide-linked homodimer (2,3). CTLA-4 belongs to the CD28 receptor family (4,5).
Reactivity: Human
Applications: IHC-Fr,IF,Flow Cyt
Shipping condition: Dry Ice
Publications: Lymphocyte activation: T-cell regulation by CTLA-4.Linsley PS, Golstein P.
Curr Biol. 1996 Apr 1;6(4):398-400.

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