Brand | Abnova |
Product type | Primary antibodies |
Reactivity | Human |
Host species | Mouse |
Applications | Flow Cyt |
Brand: | Abnova |
Reference: | MAB4598 |
Product name: | CD8 monoclonal antibody, clone MEM-31 (PE) |
Product description: | Mouse monoclonal antibody raised against native CD8. |
Clone: | MEM-31 |
Isotype: | IgG2a |
Gene id: | 925|926 |
Gene name: | CD8A |
Gene alias: | CD8|Leu2|MAL|p32 |
Gene description: | CD8a molecule |
Immunogen: | Native purified CD8 from Crude thymus membrane fraction. |
Form: | Liquid |
Recommend dilutions: | Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension) The optimal working dilution should be determined by the end user. |
Storage buffer: | In PBS (0.2% BSA, 0.09% sodium azide) |
Storage instruction: | Store in the dark at 4°C. Do not freeze. Avoid prolonged exposure to light. Aliquot to avoid repeated freezing and thawing. |
Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Conjugate tag: | PE |
Product type: | Primary antibodies |
Host species: | Mouse |
Specificity: | This antibody recognizes a conformationally-dependent epitope of CD8, a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 is a disulfide-linked dimer and exists as a CD8 alpha/alpha homodimer or CD8 alpha/beta heterodimer (each monomer approx. 32-34 KDa). This antibody does not react with formaldehyde-fixed cells; negative in Western Blot application. |
Reactivity: | Human |
Applications: | Flow Cyt |
Shipping condition: | Blue Ice |
Publications: | CD8 Raft localization is induced by its assembly into CD8alpha beta heterodimers, Not CD8alpha alpha homodimers.Pang DJ, Hayday AC, Bijlmakers MJ. J Biol Chem. 2007 May 4;282(18):13884-94. Epub 2007 Mar 6. |