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Data sheet of CD8 monoclonal antibody, clone MEM-31 (PE)
| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Host species | Mouse |
| Applications | Flow Cyt |
More info about CD8 monoclonal antibody, clone MEM-31 (PE)
| Brand: | Abnova |
| Reference: | MAB4598 |
| Product name: | CD8 monoclonal antibody, clone MEM-31 (PE) |
| Product description: | Mouse monoclonal antibody raised against native CD8. |
| Clone: | MEM-31 |
| Isotype: | IgG2a |
| Gene id: | 925|926 |
| Gene name: | CD8A |
| Gene alias: | CD8|Leu2|MAL|p32 |
| Gene description: | CD8a molecule |
| Immunogen: | Native purified CD8 from Crude thymus membrane fraction. |
| Form: | Liquid |
| Recommend dilutions: | Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In PBS (0.2% BSA, 0.09% sodium azide) |
| Storage instruction: | Store in the dark at 4°C. Do not freeze. Avoid prolonged exposure to light. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Conjugate tag: | PE |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Specificity: | This antibody recognizes a conformationally-dependent epitope of CD8, a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 is a disulfide-linked dimer and exists as a CD8 alpha/alpha homodimer or CD8 alpha/beta heterodimer (each monomer approx. 32-34 KDa). This antibody does not react with formaldehyde-fixed cells; negative in Western Blot application. |
| Reactivity: | Human |
| Applications: | Flow Cyt |
| Shipping condition: | Blue Ice |
| Publications: | CD8 Raft localization is induced by its assembly into CD8alpha beta heterodimers, Not CD8alpha alpha homodimers.Pang DJ, Hayday AC, Bijlmakers MJ. J Biol Chem. 2007 May 4;282(18):13884-94. Epub 2007 Mar 6. |