Brand | Abnova |
Product type | Primary antibodies |
Reactivity | Human |
Host species | Mouse |
Applications | WB,IP,Flow Cyt |
Brand: | Abnova |
Reference: | MAB4501 |
Product name: | ENG monoclonal antibody, clone MEM-226 (FITC) |
Product description: | Mouse monoclonal antibody raised against recombinant ENG. |
Clone: | MEM-226 |
Isotype: | IgG2a |
Gene id: | 2022 |
Gene name: | ENG |
Gene alias: | CD105|END|FLJ41744|HHT1|ORW|ORW1 |
Gene description: | endoglin |
Immunogen: | Recombinant protein corresponding to human ENG. |
Form: | Liquid |
Recommend dilutions: | Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension) The optimal working dilution should be determined by the end user. |
Storage buffer: | In PBS (0.2% BSA, 0.09% sodium azide) |
Storage instruction: | Store in the dark at 4°C. Do not freeze. Avoid prolonged exposure to light. Aliquot to avoid repeated freezing and thawing. |
Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Conjugate tag: | FITC |
Product type: | Primary antibodies |
Host species: | Mouse |
Antigen species / target species: | Human |
Specificity: | This antibody recognizes CD105 (Endoglin), a 180 KDa type I integral membrane homodimer glycoprotein expressed on vascular endothelial cells (small and large vessels), activated monocytes and tissue macrophages, stromal cells of certain tissues including bone marrow, pre-B lymphocytes in fetal marrow and erythroid precursors in fetal and adult bone marrow; it is also present on syncytiotrophoblast on placenta throughout pregnancy. |
Reactivity: | Human |
Application image: | ![]() |
Application image note: | Surface staining of HUVEC (human umbilical vein endothelial cells) with ENG monoclonal antibody, clone MEM-226 (FITC) (Cat # MAB4501). Total viable cells were used for analysis. |
Applications: | WB,IP,Flow Cyt |
Shipping condition: | Blue Ice |
Publications: | CD105 inhibits transforming growth factor-beta-Smad3 signalling.Guo B, Slevin M, Li C, Parameshwar S, Liu D, Kumar P, Bernabeu C, Kumar S. Anticancer Res. 2004 May-Jun;24(3a):1337-45. |