Brand | Abnova |
Product type | Primary antibodies |
Reactivity | Human |
Host species | Mouse |
Applications | Flow Cyt |
Brand: | Abnova |
Reference: | MAB4471 |
Product name: | FAS monoclonal antibody, clone LT95 (FITC) |
Product description: | Mouse monoclonal antibody raised against native FAS. |
Clone: | LT95 |
Isotype: | IgG1 |
Gene id: | 355 |
Gene name: | FAS |
Gene alias: | ALPS1A|APO-1|APT1|CD95|FAS1|FASTM|TNFRSF6 |
Gene description: | Fas (TNF receptor superfamily, member 6) |
Immunogen: | Native purified FAS from human T cell lymphoma cell line HUT-78. |
Form: | Liquid |
Recommend dilutions: | Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension) The optimal working dilution should be determined by the end user. |
Storage buffer: | In PBS (0.2% BSA, 0.09% sodium azide) |
Storage instruction: | Store in the dark at 4°C. Do not freeze. Avoid prolonged exposure to light. Aliquot to avoid repeated freezing and thawing. |
Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Conjugate tag: | FITC |
Product type: | Primary antibodies |
Host species: | Mouse |
Antigen species / target species: | Human |
Specificity: | This antibody reacts with CD95 (Fas/APO-1), a 46 KDa single chain type I glycoprotein of the tumour necrosis factor/nerve growth factor (TNF/NGF) receptor superfamily, expressed on a variety of normal and neoplastic cells. It seems that This antibody does not induce Fas mediated apoptosis, although it cross-blocks anti-Fas DX2 antibody that recognizes a functional epitope of Fas molecule. |
Reactivity: | Human |
Applications: | Flow Cyt |
Shipping condition: | Blue Ice |
Publications: | Fas signal links innate and adaptive immunity by promoting dendritic-cell secretion of CC and CXC chemokines.Guo Z, Zhang M, Tang H, Cao X. Blood. 2005 Sep 15;106(6):2033-41. Epub 2005 Jun 7. |