CD46 monoclonal antibody, clone MEM-258 (PE) View larger

CD46 monoclonal antibody, clone MEM-258 (PE)

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Data sheet of CD46 monoclonal antibody, clone MEM-258 (PE)

BrandAbnova
Product typePrimary antibodies
ReactivityBovine,Human
Host speciesMouse
ApplicationsWB,IP,Flow Cyt

More info about CD46 monoclonal antibody, clone MEM-258 (PE)

Brand: Abnova
Reference: MAB4442
Product name: CD46 monoclonal antibody, clone MEM-258 (PE)
Product description: Mouse monoclonal antibody raised against native CD46.
Clone: MEM-258
Isotype: IgG1
Gene id: 4179
Gene name: CD46
Gene alias: MCP|MGC26544|MIC10|TLX|TRA2.10
Gene description: CD46 molecule, complement regulatory protein
Immunogen: Native purified CD46 from human T cell line HPB-ALL.
Form: Liquid
Recommend dilutions: Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension)
The optimal working dilution should be determined by the end user.
Storage buffer: In PBS (0.2% BSA, 0.09% sodium azide)
Storage instruction: Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.
Note: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Conjugate tag: PE
Product type: Primary antibodies
Host species: Mouse
Antigen species / target species: Human
Specificity: This antibody recognizes an epitope on SCR4 (the membrane-proximal SCR) domain of CD46 (Membrane cofactor protein). CD46 is 56-66 KDa dimeric transmembrane protein expressed on T and B lymphocytes, platelets, monocytes, granulocytes, endothelial cells, epithelial cells and fibroblast; it is negative on erythrocytes.
Reactivity: Bovine,Human
Application image: MAB4442-84-232-1.jpg
Application image note: Surface staining of human peripheral blood cells with CD46 monoclonal antibody, clone MEM-258 (PE) (Cat # MAB4442).
Applications: WB,IP,Flow Cyt
Shipping condition: Blue Ice
Publications: Ligation of the cell surface receptor, CD46, alters T cell polarity and response to antigen presentation.Oliaro J, Pasam A, Waterhouse NJ, Browne KA, Ludford-Menting MJ, Trapani JA, Russell SM.
Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18685-90. Epub 2006 Nov 20.

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