Brand | Abnova |
Product type | Primary antibodies |
Reactivity | Human |
Host species | Mouse |
Applications | Flow Cyt |
Brand: | Abnova |
Reference: | MAB4431 |
Product name: | ITGA2B monoclonal antibody, clone MEM-06 (PE) |
Product description: | Mouse monoclonal antibody raised against native ITGA2B. |
Clone: | MEM-06 |
Isotype: | IgG1 |
Gene id: | 3674 |
Gene name: | ITGA2B |
Gene alias: | CD41|CD41B|GP2B|GPIIb|GTA|HPA3 |
Gene description: | integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) |
Immunogen: | Native purified ITGA2B from leukocytes of a patient suffering from a LGL-type leukemia. |
Form: | Liquid |
Recommend dilutions: | Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension) The optimal working dilution should be determined by the end user. |
Storage buffer: | In PBS (0.2% BSA, 0.09% sodium azide) |
Storage instruction: | Store in the dark at 4°C. Do not freeze. Avoid prolonged exposure to light. Aliquot to avoid repeated freezing and thawing. |
Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Conjugate tag: | PE |
Product type: | Primary antibodies |
Host species: | Mouse |
Antigen species / target species: | Human |
Specificity: | This antibody reacts with CD41 (GPIIb), a transmembrane glycoprotein (integrin family) composed of two chains GPIIb alpha (heavy chain; 120 KDa) and GPIIb beta (light chain; 23 KDa). CD41 is mainly expressed on platelets and megakaryocytes. |
Reactivity: | Human |
Application image: | ![]() |
Application image note: | Surface staining of human platelets with ITGA2B monoclonal antibody, clone MEM-06 (PE) (Cat # MAB4431). |
Applications: | Flow Cyt |
Shipping condition: | Blue Ice |
Publications: | CD41-YFP mice allow in vivo labeling of megakaryocytic cells and reveal a subset of platelets hyperreactive to thrombin stimulation.Zhang J, Varas F, Stadtfeld M, Heck S, Faust N, Graf T. Exp Hematol. 2007 Mar;35(3):490-499. |