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Data sheet of MS4A1 monoclonal antibody, clone LT20 (FITC)
| Brand | Abnova |
| Product type | Primary antibodies |
| Reactivity | Human |
| Host species | Mouse |
| Applications | Flow Cyt |
More info about MS4A1 monoclonal antibody, clone LT20 (FITC)
| Brand: | Abnova |
| Reference: | MAB4385 |
| Product name: | MS4A1 monoclonal antibody, clone LT20 (FITC) |
| Product description: | Mouse monoclonal antibody raised against native MS4A1. |
| Clone: | LT20 |
| Isotype: | IgG2a |
| Gene id: | 931 |
| Gene name: | MS4A1 |
| Gene alias: | B1|Bp35|CD20|LEU-16|MGC3969|MS4A2|S7 |
| Gene description: | membrane-spanning 4-domains, subfamily A, member 1 |
| Immunogen: | Native purified MS4A1 from normal human lymphocytes from lymph node. |
| Form: | Liquid |
| Recommend dilutions: | Flow Cytometry (20 ul in human blood cells 100 ul in whole blood or 106 cells in a suspension) The optimal working dilution should be determined by the end user. |
| Storage buffer: | In PBS (0.2% BSA, 0.09% sodium azide) |
| Storage instruction: | Store in the dark at 4°C. Do not freeze. Avoid prolonged exposure to light. Aliquot to avoid repeated freezing and thawing. |
| Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
| Conjugate tag: | FITC |
| Product type: | Primary antibodies |
| Host species: | Mouse |
| Antigen species / target species: | Human |
| Specificity: | This antibody reacts with CD20 (Bp35), a 33-37 KDa non-glycosylated membrane receptor with four transmembrane domains, expressed on B lymphocytes (it is lost on plasma cells), follicular dendritic cells, and at low levels on peripheral blood T lymphocytes. |
| Reactivity: | Human |
| Application image: |  |
| Application image note: | Surface staining of human peripheral blood cells with MS4A1 monoclonal antibody, clone LT20 (FITC) (Cat # MAB4385). |
| Applications: | Flow Cyt |
| Shipping condition: | Blue Ice |
| Publications: | Alanine-170 and proline-172 are critical determinants for extracellular CD20 epitopes; heterogeneity in the fine specificity of CD20 monoclonal antibodies is defined by additional requirements imposed by both amino acid sequence and quaternary structure.Polyak MJ, Deans JP. Blood. 2002 May 1;99(9):3256-62. |