Brand: | Abnova |
Reference: | MAB3630 |
Product name: | HLA-E monoclonal antibody, clone MEM-E/06 |
Product description: | Mouse monoclonal antibody raised against recombinant HLA-E. |
Clone: | MEM-E/06 |
Isotype: | IgG1 |
Gene id: | 3133 |
Gene name: | HLA-E |
Gene alias: | DKFZp686P19218|EA1.2|EA2.1|HLA-6.2|MHC|QA1 |
Gene description: | major histocompatibility complex, class I, E |
Immunogen: | Recombinant protein corresponding to human HLA-E. |
Form: | Liquid |
Concentration: | 1 mg/mL |
Recommend dilutions: | The optimal working dilution should be determined by the end user. |
Storage buffer: | In TBS, pH 8.0 (0.09% sodium azide) |
Storage instruction: | Store at 4°C. Do not freeze. |
Note: | This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only. |
Product type: | Primary antibodies |
Host species: | Mouse |
Antigen species / target species: | Human |
Specificity: | This antibody recognized native surface-expressed HLA-E, but not denaturated heavy chain of HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib; nonclassical) and it is expressed on many types of the human cells. The published results showed that This antibody cross-reacts with some classical MHC ClassI molecules (HLA-A3, -A11, -B7). However, the recent Workshop I Session on the 3rd International Conference on HLA-G (Paris, July 2003) confirmed that This antibody exhibits much broader cross-reactivity classical MHC Class I antigens, namely with HLA-A24, -A32,-B8, -B15, -B27, -B35, -B44, -B54, -C3, -C4, -C5, -C7. |
Reactivity: | Human,Primates |
Applications: | IP,Flow Cyt |
Shipping condition: | Blue Ice |
Publications: | Characterization of monoclonal antibodies recognizing HLA-G or HLA-E: new tools to analyze the expression of nonclassical HLA class I molecules.Menier C, Saez B, Horejsi V, Martinozzi S, Krawice-Radanne I, Bruel S, Le Danff C, Reboul M, Hilgert I, Rabreau M, Larrad ML, Pla M, Carosella ED, Rouas-Freiss N. Hum Immunol. 2003 Mar;64(3):315-26. |